The international popularity of herbal remedies has recently outpaced quality information on the utilization and dosing of these compounds. This book fills a void in the literature by offering an authoritative overview of the mechanisms of herbal remedies and their impact on standard medications. It offers a practical approach that focuses not only on specific drug interactions, but the mechanisms behind those interactions and their clinical significance. With contributions from leading experts on the subject, this text examines the overall use of herbs, includes sections on individual herbs, and considers pertinent regulatory issues and concerns in industry.
Table of Contents
The Landscape of Herbal Medicine Utilization and Safety. Drug Interactions with Herbal Products. In Vitro Studies with Natural Health Products. St. John's Wort and Echinacea Drug Interactions. Garlic, Ginkgo, and Ginseng: Herb-Drug Interactions. A Review of Chinese Herb-Drug Interactions. Grapefruit Juice Interactions. Herb Quality Assurance. Pharmocokinetics of Herbal Products. Labeling of Drug Interactions. Post Marketing Reporting System Evaluation. Post-marketing reports on St. John's Wort. Post Marketing reports on Grapefruit Juice. Botanicals as Drugs, a US Perspective. Development of Herbal Products as Pharmaceutical Agents.
"…The focus of this book is to provide an improved understanding of the scientific issues involved in interactions of botanicals and drugs and to assist in further development of botanical products. The intent of the book is important, given the growing use of herbal products….Discussions by experts at the Food and Drug Administration on the regulatory issues posed by development of botanical products are well documented."
-Doody's Review Services
"…provides a succinct and practical overview of the scientific and regulatory perspectives on dietary supplements…a particular strength of this book is the expertise and diversity of the contributors…The FDA perspective is a welcome bonus and provides valuable insight and a rational framework for the existence of botanical products in the context of the US 'drug world.'…Not only is this book a useful guide for clinical pharmacologists with an interest in botanicals and healthcare practitioners who advise patients on botanical use, but it also will prove to be a valuable resource for scientists who study botanical-drug interactions and others who already have a great deal of expertise in this field."
-Clinical Pharmacology & Therapeutics